منابع مشابه
Treadmill exercise alleviates depressive symptoms in rotenone-induced Parkinson disease rats
Parkinson disease (PD) is characterized by selective loss of the dopaminergic neurons. The symptoms of depression following PD are closely associated with reduced activity of the serotonergic system in the dorsal raphe. We explored the antidepressive effect of exercise and its possible mechanism using the rotenone-induced PD rats. PD rats were induced by subcutaneously injection with rotenone f...
متن کاملEffects of Voluntary Exercise on Motor Function in Parkinson\'s disease Model of Rats
Background. Previous surveys have shown that motor deficits precede the classical motor symptoms seen in Parkinson’s disease (PD) and that physical exercise may have beneficial effects on PD. Objectives. Here, we evaluated the potential of voluntary exercise to improve motor deficit in experimentally-induced Parkinson’s disease (6-OHDA) rats. Methods. Forty adult Wistar rats were ...
متن کاملThe effect of low dose amphetamine in rotenone-induced toxicity in a mice model of Parkinson’s disease
Objective(s): The effects of low dose amphetamine on oxidative stress and rotenone-induced neurotoxicity and liver injury were examined in vivo in a mice model of Parkinson’s disease. Materials and Methods: Male mice were treated with rotenone (1.5 mg/kg, every other day for two weeks, subcutaneously). Mice received either the vehicle or...
متن کاملPaeonol Protection Against Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson\'s Disease
Introduction: Parkinsonchr('39')s disease (PD) presentations comprise frequent movement disorders in the elderly with various symptoms consisting of motor and non-motor complications. Paeonol is a phenolic chemical agent that has shown antioxidant and anti-inflammatory effects in different disorders and promising effects on metabotropic glutamate receptors (mGluR)- and GABAA-mediated neurotrans...
متن کاملA Mouse Model for Parkinson Disease
August 2005 | Volume 3 | Issue 8 | e286 | e281 According to folklore, Polynesians originated from a mythical homeland called Hawaiki. The existence of such a place, however, as well as its location, has been the subject of much speculation. Signifi cant research efforts have attempted to elucidate these claims through archeological, linguistic, and, more recently, biological evidence. Jean Trej...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2005
ISSN: 0021-9258
DOI: 10.1074/jbc.m508628200